DISCOVER METRIC.

At Metric, we’re redefining the way functional proteins are designed. Our mission is to shift protein discovery away from trial and error and toward precision engineering by design. Powered by advanced computational modeling and experimental platforms, our technology enables researchers to design proteins with desired functional properties, including affinity maturation, tissue selectivity, cross-species compatibility, pH sensitivity, and cell function outcomes like killing or agonism, all within a single experiment.
Our approach empowers teams to extract more value from each assay by simultaneously optimizing multiple molecular traits. This significantly accelerates the pace of discovery and unlocks design possibilities that were previously unimaginable.
Whether you're building the next generation of biologics or tackling a complex molecular challenge, Metric delivers intelligent, function-first protein solutions that move science forward.
Pioneers of quantitative biophysics from high-throughput biology
From the beginnings of computational genomics to the NGS/-omics era, we have designed category-defining, state-of-the-art methods for sequence-to-function analyses

Jiah Pearson-Leary, PhD
CEO
Researcher and strategy consultant to 20+ Biopharma companies; 10+ years drug discovery and business and commercial development.
Children's Hospital of Philadelphia
inThought Research
Centron Bio

Chaitanya Rastogi, PhD
Co-Founder
PhD in Computational Biology at Columbia, BS, MS in Physics and Business at Caltech
Caltech
Columbia University

Harmen Bussemaker, PhD
Co-Founder
Professor of Biological Sciences and Systems Biology at Columbia
Universiteit Utrecht
The Rockefeller University
Columbia University
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